Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0W0TW
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| Former ID |
DCL001235
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| Drug Name |
S-349572
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| Drug Type |
Small molecular drug
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| Indication | Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] | Phase 3 | [1] | ||
| Company |
Shionogi & GlaxoSmithKline
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| Structure |
|
Download2D MOL |
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| Formula |
C20H19F2N3O5
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| Canonical SMILES |
CC1CCOC2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)<br />F)F)O
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| InChI |
1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1
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| InChIKey |
RHWKPHLQXYSBKR-BMIGLBTASA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID |
96100998, 123055423, 124361075, 124361082, 124361088, 135268073, 135273443, 135626786, 136340316, 136349541, 136367672, 136920429, 144115916, 152258477, 160647312, 160693271, 162011364, 162038052, 162202774, 163677014, 164043525, 164193963, 164347381, 170484068, 170484069, 170484070, 170503405, 174007466, 174525979, 175427161, 178103937, 184812380, 189622844, 198935766, 198993556, 223382143, 223705174, 226460906, 242590891, 248390482, 250184664, 252110159, 252224388, 252451605
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| Target and Pathway | |||||
| Target(s) | HIV integrase | Target Info | Inhibitor | [2], [1] | |
| References | |||||
| REF 1 | Clinical pipeline report, company report or official report of Shionogi (2011). | ||||
| REF 2 | 2013 FDA drug approvals. Nat Rev Drug Discov. 2014 Feb;13(2):85-9. | ||||
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