Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05BBQ
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| Former ID |
DIB005492
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| Drug Name |
RP-66364
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| Synonyms |
RP-60532; RP-69929
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| Indication | Inflammatory disease [ICD9: 140-229, 147, 173, 573.3, 710-719; ICD10:C11, C44, K75.9, M00-M25] | Terminated | [1] | ||
| Company |
Rhone-Poulenc SA
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
c1(c(oc(n1)CCCCCCc1nn[nH]n1)c1ccc(cc1)OC)c1ccc(cc1)OC
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| CAS Number |
CAS 186912-92-5
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| Target and Pathway | |||||
| Target(s) | Leukotriene B4 receptor 1 | Target Info | Modulator | [2] | |
| Cyclooxygenase | Target Info | Modulator | [2] | ||
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| Reactome | Leukotriene receptors | ||||
| G alpha (q) signalling events | |||||
| WikiPathways | Nucleotide GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Spinal Cord Injury | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003795) | ||||
| REF 2 | WO patent application no. 1997,0297,75, Compositions comprising a cyclooxygenase-2 inhibitor and a leukotriene b4 receptor antagonist. | ||||
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