Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02GLD
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| Former ID |
DIB008204
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| Drug Name |
MF-101
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| Synonyms |
Liquiritigenin; Menerba; DW-700; DW-700); Menopause Formula-101; Estrogen receptor beta agonist (menopausal symptoms), Bionovo; Liquiritigenin (menopausal symptoms), Bionovo
|
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| Indication | Hepatitis virus infection [ICD9: 573.3; ICD10:K75.9] | Phase 3 | [1] | ||
| Company |
Bionovo Inc; Daewon Pharm Co Ltd
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| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
c12c(C(=O)C[C@H](O1)c1ccc(cc1)O)ccc(c2)O
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| CAS Number |
CAS 578-86-9
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| Target and Pathway | |||||
| Target(s) | Estrogen receptor beta | Target Info | Antagonist | [2] | |
| KEGG Pathway | Estrogen signaling pathway | ||||
| Prolactin signaling pathway | |||||
| Pathway Interaction Database | Plasma membrane estrogen receptor signaling | ||||
| Validated nuclear estrogen receptor beta network | |||||
| Validated nuclear estrogen receptor alpha network | |||||
| Reactome | Nuclear Receptor transcription pathway | ||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| Ovarian Infertility Genes | |||||
| Integrated Pancreatic Cancer Pathway | |||||
| Nuclear Receptors | |||||
| References | |||||
| REF 1 | ClinicalTrials.gov (NCT00906308) A Study of MF101 in Postmenopausal Women. U.S. National Institutes of Health. | ||||
| REF 2 | MF101, a selective estrogen receptor beta modulator for the treatment of menopausal hot flushes: a phase II clinical trial. Menopause. 2009 May-Jun;16(3):458-65. | ||||
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