Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D04YLU
|
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| Former ID |
DIB008025
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| Drug Name |
AZ-599
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| Synonyms |
CB1 agonist (pain), AstraZeneca
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| Indication | Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] | Investigative | [1] | ||
| Company |
AstraZeneca plc
|
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
O=S(=O)(n1c2ccc(C(=O)N3CCC(CC3)C)cc2c2c1CCN(C1CCOCC1)C2<br />)CC
|
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| Target and Pathway | |||||
| Target(s) | Cannabinoid receptor 1 | Target Info | Agonist | [1] | |
| KEGG Pathway | Rap1 signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Retrograde endocannabinoid signaling | |||||
| PANTHER Pathway | Endogenous cannabinoid signaling | ||||
| Pathway Interaction Database | N-cadherin signaling events | ||||
| Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Small Ligand GPCRs | |||||
| BDNF signaling pathway | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 56). | ||||
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