Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0N0VW
|
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| Former ID |
DIB002437
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| Drug Name |
IDN-5174
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| Synonyms |
Camptothecin analogs (anticancer); IDN-5174; Camptothecin analogs (anticancer), Indena
|
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| Indication | Cancer [ICD9: 140-229; ICD10:C00-C96] | Investigative | [1] | ||
| Company |
Indena SpA
|
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| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
n12c(c3c([C@H]2N=[N+]=[N-])cc2c(n3)cccc2)cc2c(c1=O)COC(<br />=O)[C@]2(O)CC
|
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| Target and Pathway | |||||
| Target(s) | Toposisomerase-1 | Target Info | Inhibitor | [1] | |
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PANTHER Pathway | DNA replication | ||||
| Pathway Interaction Database | Caspase Cascade in Apoptosis | ||||
| WikiPathways | Integrated Pancreatic Cancer Pathway | ||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2636). | ||||
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