Drug General Information
Drug ID
D04MSM
Former ID
DIB013444
Drug Name
Carbamazepine
Synonyms
Carbamazepine (iv, epilepsy); Carbamazepine (iv, epilepsy), Lundbeck; Carbamazepine (iv, epilepsy), Ovation Pharmaceuticals
Drug Type
Small molecular drug
Indication Epilepsy [ICD10:G40] Approved [1], [2]
Company
Lundbeck Inc
Structure
Download
2D MOL

3D MOL

Formula
C15H12N2O
InChI
InChI=1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)
InChIKey
FFGPTBGBLSHEPO-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Sodium channel Target Info Modulator [3]
KEGG Pathway Dopaminergic synapse
Reactome Interaction between L1 and Ankyrins
References
REF 1Thirty years of clinical experience with carbamazepine in the treatment of bipolar illness: principles and practice. CNS Drugs. 2007;21(1):47-71.
REF 2(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5339).
REF 3Sidedness of carbamazepine accessibility to voltage-gated sodium channels. Mol Pharmacol. 2014 Feb;85(2):381-7.

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