TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T94788 Branched-chain-amino-acid transaminase 2 B2G4LJ 3-Methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamide Investigative 42959251 C10H14N2O2S 226.3 CC1CC2=C(C(=CC=C2)S(=O)(=O)N)NC1 IC50 > 1258925.41 nM Non binder T94788 Branched-chain-amino-acid transaminase 2 B4UXB2 2,1,3-Benzothiadiazol-5-ylmethanol Investigative 2776294 C7H6N2OS 166.2 C1=CC2=NSN=C2C=C1CO IC50 > 1258925.41 nM Non binder T94788 Branched-chain-amino-acid transaminase 2 B7DJE3 2-(1,2-Benzisoxazol-3-yl)acetic acid Investigative 301729 C9H7NO3 177.16 C1=CC=C2C(=C1)C(=NO2)CC(=O)O IC50 > 1258925.41 nM Non binder T94788 Branched-chain-amino-acid transaminase 2 B91CUV 2-Ethoxy-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile Investigative 122190027 C10H10N4O2 218.21 CCOC1=C(C2=NC(=CC(=O)N2N1)C)C#N IC50 = 501187.23 nM Non binder T94788 Branched-chain-amino-acid transaminase 2 BC5O7A 5-Methyl-4-oxo-N-pyridin-3-yl-3H-thieno[2,3-d]pyrimidine-6-carboxamide Investigative 127029155 C13H10N4O2S 286.31 CC1=C(SC2=C1C(=O)NC=N2)C(=O)NC3=CN=CC=C3 IC50 = 251188.64 nM Non binder T94788 Branched-chain-amino-acid transaminase 2 BDXS62 2-Hydroxy-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide Investigative 16770079 C12H15NO2 205.25 C1CC(C2=CC=CC=C2C1)NC(=O)CO IC50 > 1258925.41 nM Non binder T94788 Branched-chain-amino-acid transaminase 2 BK9IR7 3,5-Dimethyl-6-(piperidine-1-carbonyl)thieno[2,3-d]pyrimidin-4-one Investigative 18108101 C14H17N3O2S 291.37 CC1=C(SC2=C1C(=O)N(C=N2)C)C(=O)N3CCCCC3 IC50 > 630957.34 nM Non binder T94788 Branched-chain-amino-acid transaminase 2 BSA53I 5-Ethyl-2-Methyl-7-Oxo-4,7-Dihydropyrazolo[1,5-A]pyrimidine-3-Carbonitrile Investigative 8030270 C10H10N4O 202.21 CCC1=CC(=O)N2C(=N1)C(=C(N2)C)C#N IC50 > 630957.34 nM Non binder T94788 Branched-chain-amino-acid transaminase 2 BUV63W (2-Hydroxy-2-phenylethyl)urea Investigative 212827 C9H12N2O2 180.2 C1=CC=C(C=C1)C(CNC(=O)N)O IC50 = 794328.23 nM Non binder T94788 Branched-chain-amino-acid transaminase 2 BVAX54 N-(Pyrimidin-5-Yl)benzamide Investigative 68971843 C11H9N3O 199.21 C1=CC=C(C=C1)C(=O)NC2=CN=CN=C2 IC50 = 1000000 nM Non binder T94788 Branched-chain-amino-acid transaminase 2 BWU58Q Benzanilide Investigative 7168 C13H11NO 197.23 C1=CC=C(C=C1)C(=O)NC2=CC=CC=C2 IC50 > 630957.34 nM Non binder T94788 Branched-chain-amino-acid transaminase 2 BYO9T1 Benzeneacetic acid, 2-[(phenylamino)carbonyl]- Investigative 11470832 C15H13NO3 255.27 C1=CC=C(C=C1)NC(=O)C2=CC=CC=C2CC(=O)O IC50 = 316227.77 nM Non binder