TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T83174 Protein kinase C iota B25JXO Chembl4203835 Investigative 145977039 C17H15N5 289.33 C1C(CN1)N2C=NC3=C2C=C(C=C3)C4=C5C=CNC5=NC=C4 IC50 = 188000 nM Poor binder T83174 Protein kinase C iota B2U1HJ 1-(Tert-Butyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Investigative 4877 C19H19N5 317.4 CC(C)(C)N1C2=NC=NC(=C2C(=N1)C3=CC=CC4=CC=CC=C43)N IC50 ~ 100000 nM Poor binder T83174 Protein kinase C iota B6FMD0 Chembl4205739 Investigative 145977626 C13H9N5 235.24 C1=CC2=NC=CN2N=C1C3=C4C=CNC4=NC=C3 IC50 = 75000 nM Poor binder T83174 Protein kinase C iota B7GHL8 Chembl4218133 Investigative 145967523 C16H11N3 245.28 C1=CC(=CC2=C1C=CN=C2)C3=C4C=CNC4=NC=C3 IC50 = 95000 nM Poor binder T83174 Protein kinase C iota B7O8KY Chembl4202899 Investigative 145975520 C15H11N3O 249.27 C1C2=C(C=CC(=C2)C3=C4C=CNC4=NC=C3)C(=O)N1 IC50 = 105000 nM Poor binder T83174 Protein kinase C iota BHO85F N'-[2-(1-Methylpyrazol-4-yl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl]ethane-1,2-diamine Investigative 89596586 C16H20N6S 328.4 CN1C=C(C=N1)C2=NC(=C3C4=C(CCCC4)SC3=N2)NCCN IC50 ~ 60000 nM Poor binder T83174 Protein kinase C iota BZ2X6C Chembl4210601 Investigative 145965697 C15H13N3O 251.28 C1COC2=C(N1)C=C(C=C2)C3=C4C=CNC4=NC=C3 IC50 = 148000 nM Poor binder