Target General Information
Target ID	T23348
Target Name	von Willebrand factor
Synonyms	VWF
Target Type	Clinical Trial
Gene Name	VWF
UniProt ID	VWF_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Thrombocytopenia
Example drug	caplacizumab			Phase 2	[532188], [1572592]
Tissue	Whole blood
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 2.47 Z-score: 2.08 P-value: 2.96E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 532188	Novel antiplatelet agents: ALX-0081, a Nanobody directed towards von Willebrand factor. J Cardiovasc Transl Res. 2013 Jun;6(3):355-63.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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