Target Information
| Target General Infomation | |||||
|---|---|---|---|---|---|
| Target ID |
T81623
|
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| Former ID |
TTDI03152
|
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| Target Name |
death-associated protein kinase 3
|
||||
| Gene Name |
DAPK3
|
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| Synonyms |
DAPK3
|
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| Target Type |
Research
|
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| UniProt ID | |||||
| Sequence |
MSTFRQEDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREE
IEREVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFL KQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGT PEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEY FSNTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKAIRRRNVRGEDSGRKPERRRLKTT RLKEYTIKSHSSLPPNNSYADFERFSKVLEEAAAAEEGLRELQRSRRLCHEDVEALAAIY EEKEAWYREESDSLGQDLRRLRQELLKTEALKRQAQEEAKGALLGTSGLKRRFSRLENRY EALAKQVASEMRFVQDLVRALEQEKLQGVECGLR |
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| Inhibitor | URMC-099 | Drug Info | [1] | ||
| References | |||||
| REF 1 | Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3. J Med Chem. 2013 Oct 24;56(20):8032-48. | ||||
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