Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01NUT
|
||||
| Former ID |
DNC010151
|
||||
| Drug Name |
Mulberrofuran D
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C29H34O4
|
||||
| Canonical SMILES |
CC(=CCCC(=CCC1=C(C=CC2=C1OC(=C2)C3=CC(=CC(=C3CC=C(C)C)O<br />)O)O)C)C
|
||||
| InChI |
1S/C29H34O4/c1-18(2)7-6-8-20(5)10-13-24-26(31)14-11-21-15-28(33-29(21)24)25-16-22(30)17-27(32)23(25)12-9-19(3)4/h7,9-11,14-17,30-32H,6,8,12-13H2,1-5H3/b20-10+
|
||||
| InChIKey |
WCJPAQJEARHLGS-KEBDBYFISA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | mRNA of Protein tyrosine phosphatase-1B | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Adherens junction | ||||
| Insulin signaling pathway | |||||
| NetPath Pathway | FSH Signaling Pathway | ||||
| PANTHER Pathway | Cadherin signaling pathway | ||||
| Pathway Interaction Database | Insulin Pathway | ||||
| Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) | |||||
| Signaling events mediated by PTP1B | |||||
| Calcineurin-regulated NFAT-dependent transcription in lymphocytes | |||||
| Signaling events mediated by TCPTP | |||||
| IGF1 pathway | |||||
| EGF receptor (ErbB1) signaling pathway | |||||
| Posttranslational regulation of adherens junction stability and dissassembly | |||||
| PDGFR-beta signaling pathway | |||||
| N-cadherin signaling events | |||||
| Reactome | Integrin alphaIIb beta3 signaling | ||||
| Regulation of IFNG signaling | |||||
| Regulation of IFNA signaling | |||||
| Growth hormone receptor signaling | |||||
| WikiPathways | Insulin Signaling | ||||
| Growth hormone receptor signaling | |||||
| Leptin signaling pathway | |||||
| Interferon gamma signaling | |||||
| Interferon alpha/beta signaling | |||||
| Integrin alphaIIb beta3 signaling | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2009 Dec 1;19(23):6759-61. Epub 2009 Oct 7.Protein tyrosine phosphatase 1B inhibitors isolated from Morus bombycis. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.