| Drug General Information |
| Drug ID |
D03MJJ
|
| Former ID |
DNC002419
|
| Drug Name |
Thiocoumarin
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C14H17NO2S
|
| Canonical SMILES |
CN(C)CCCOC1=CC(=O)SC2=CC=CC=C21
|
| InChI |
1S/C14H17NO2S/c1-15(2)8-5-9-17-12-10-14(16)18-13-7-4-3-6-11(12)13/h3-4,6-7,10H,5,8-9H2,1-2H3
|
| InChIKey |
DIOZFKOOIBATNZ-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| PubChem Substance ID |
|
| Target and Pathway |
| Target(s) |
Nitric oxide synthase, inducible |
Target Info |
Inhibitor |
[1]
|
|---|
|
BioCyc Pathway
|
Citrulline-nitric oxide cycle
|
|
KEGG Pathway
|
Arginine biosynthesis
|
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Arginine and proline metabolism
|
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Metabolic pathways
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Calcium signaling pathway
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HIF-1 signaling pathway
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Peroxisome
|
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Salmonella infection
|
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Pertussis
|
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Leishmaniasis
|
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Chagas disease (American trypanosomiasis)
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Toxoplasmosis
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Amoebiasis
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Tuberculosis
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Pathways in cancer
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Small cell lung cancer
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NetPath Pathway
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IL1 Signaling Pathway
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IL2 Signaling Pathway
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Pathway Interaction Database
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IL12-mediated signaling events
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Alpha9 beta1 integrin signaling events
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ATF-2 transcription factor network
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IL23-mediated signaling events
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Signaling mediated by p38-alpha and p38-beta
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HIF-1-alpha transcription factor network
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Reactome
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ROS production in response to bacteria
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Nitric oxide stimulates guanylate cyclase
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WikiPathways
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Type II interferon signaling (IFNG)
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Spinal Cord Injury
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AGE/RAGE pathway
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|
Effects of Nitric Oxide
|
| References |
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
|---|
