Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05EGR
|
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| Former ID |
DNC002848
|
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| Drug Name |
Bis-Napthyl Beta-Ketophosphonic Acid
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C22H17O4P
|
||||
| Canonical SMILES |
C1=CC=C2C=C(C=CC2=C1)C(=O)C(C3=CC=CC4=CC=CC=C43)P(=O)(O<br />)O
|
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| InChI |
1S/C22H17O4P/c23-21(18-13-12-15-6-1-2-8-17(15)14-18)22(27(24,25)26)20-11-5-9-16-7-3-4-10-19(16)20/h1-14,22H,(H2,24,25,26)/t22-/m1/s1
|
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| InChIKey |
OFHMUASCSJJNNA-JOCHJYFZSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Cathepsin G | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Lysosome | |||||
| Renin-angiotensin system | |||||
| Amoebiasis | |||||
| Systemic lupus erythematosus | |||||
| Pathway Interaction Database | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling | ||||
| Reactome | Degradation of the extracellular matrix | ||||
| Activation of Matrix Metalloproteinases | |||||
| Metabolism of Angiotensinogen to Angiotensins | |||||
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | |||||
| WikiPathways | ACE Inhibitor Pathway | ||||
| Regulation of Insulin-like Growth Factor (IGF) Transport and Uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | |||||
| References | |||||
| REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | ||||
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