Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07JYF
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| Former ID |
DNC005121
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| Drug Name |
6-Nitro-benzothiazole-2-sulfonic acid amide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C7H5N3O4S2
|
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| Canonical SMILES |
C1=CC2=C(C=C1[N+](=O)[O-])SC(=N2)S(=O)(=O)N
|
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| InChI |
1S/C7H5N3O4S2/c8-16(13,14)7-9-5-2-1-4(10(11)12)3-6(5)15-7/h1-3H,(H2,8,13,14)
|
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| InChIKey |
VDPWQQORTOWPSP-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Carbonic anhydrase II | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Nitrogen metabolism | ||||
| Proximal tubule bicarbonate reclamation | |||||
| Collecting duct acid secretion | |||||
| Gastric acid secretion | |||||
| Pancreatic secretion | |||||
| Bile secretion | |||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| EGFR1 Signaling Pathway | |||||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | ||||
| Erythrocytes take up oxygen and release carbon dioxide | |||||
| Reversible hydration of carbon dioxide | |||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | ||||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | |||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2004 Nov 15;14(22):5703-7.Carbonic anhydrase inhibitors: inhibition of human cytosolic isozyme II and mitochondrial isozyme V with a series of benzene sulfonamide derivatives. | ||||
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