Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07PSW
|
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| Former ID |
DNC004077
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| Drug Name |
N-(4-Phenyl-pyridin-2-yl)-guanidine
|
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C12H12N4
|
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| Canonical SMILES |
C1=CC=C(C=C1)C2=CC(=NC=C2)N=C(N)N
|
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| InChI |
1S/C12H12N4/c13-12(14)16-11-8-10(6-7-15-11)9-4-2-1-3-5-9/h1-8H,(H4,13,14,15,16)
|
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| InChIKey |
LQYVUDQYWIIZAV-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Tissue-type plasminogen activator | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Complement and coagulation cascades | ||||
| Transcriptional misregulation in cancer | |||||
| NetPath Pathway | IL5 Signaling Pathway | ||||
| PANTHER Pathway | Blood coagulation | ||||
| Plasminogen activating cascade | |||||
| Pathway Interaction Database | amb2 Integrin signaling | ||||
| Beta2 integrin cell surface interactions | |||||
| PathWhiz Pathway | Coagulation | ||||
| Reactome | Dissolution of Fibrin Clot | ||||
| WikiPathways | Senescence and Autophagy in Cancer | ||||
| Complement and Coagulation Cascades | |||||
| Endochondral Ossification | |||||
| Blood Clotting Cascade | |||||
| Dissolution of Fibrin Clot | |||||
| Folate Metabolism | |||||
| Vitamin B12 Metabolism | |||||
| Selenium Micronutrient Network | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2002 Jan 21;12(2):181-4.Selective urokinase-type plasminogen activator (uPA) inhibitors. Part 1: 2-Pyridinylguanidines. | ||||
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