| Drug General Information |
| Drug ID |
D07QSM
|
| Former ID |
DNC009594
|
| Drug Name |
Methyl 2-(2-oxohexadecanamido)acetate
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C19H35NO4
|
| Canonical SMILES |
CCCCCCCCCCCCCCC(=O)C(=O)NCC(=O)OC
|
| InChI |
1S/C19H35NO4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-17(21)19(23)20-16-18(22)24-2/h3-16H2,1-2H3,(H,20,23)
|
| InChIKey |
PZEVUHTWLYMLFR-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Cytosolic phospholipase A2 |
Target Info |
Inhibitor |
[1]
|
|---|
|
BioCyc Pathway
|
Phospholipases
|
|
KEGG Pathway
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Glycerophospholipid metabolism
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Ether lipid metabolism
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Arachidonic acid metabolism
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Linoleic acid metabolism
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alpha-Linolenic acid metabolism
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Metabolic pathways
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MAPK signaling pathway
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Ras signaling pathway
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Vascular smooth muscle contraction
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VEGF signaling pathway
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Platelet activation
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Fc epsilon RI signaling pathway
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Fc gamma R-mediated phagocytosis
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Glutamatergic synapse
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Serotonergic synapse
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Long-term depression
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Inflammatory mediator regulation of TRP channels
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GnRH signaling pathway
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Ovarian steroidogenesis
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Oxytocin signaling pathway
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Choline metabolism in cancer
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NetPath Pathway
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TCR Signaling Pathway
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PANTHER Pathway
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Angiogenesis
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Endothelin signaling pathway
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Inflammation mediated by chemokine and cytokine signaling pathway
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Oxidative stress response
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VEGF signaling pathway
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CCKR signaling map ST
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Pathway Interaction Database
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Fc-epsilon receptor I signaling in mast cells
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Endothelins
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PDGFR-beta signaling pathway
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Signaling mediated by p38-alpha and p38-beta
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PathWhiz Pathway
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Fc Epsilon Receptor I Signaling in Mast Cells
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Reactome
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Acyl chain remodelling of PC
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Acyl chain remodelling of PE
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Acyl chain remodelling of PI
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ADP signalling through P2Y purinoceptor 1
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Platelet sensitization by LDL
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WikiPathways
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Prostaglandin Synthesis and Regulation
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p38 MAPK Signaling Pathway
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Glycerophospholipid biosynthesis
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Arachidonic acid metabolism
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PDGF Pathway
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Integrated Pancreatic Cancer Pathway
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AGE/RAGE pathway
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Opioid Signalling
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Signal amplification
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Platelet homeostasis
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| References |
| REF 1 | Bioorg Med Chem. 2008 Dec 15;16(24):10257-69. Epub 2008 Nov 1.Structure-activity relationships of natural and non-natural amino acid-based amide and 2-oxoamide inhibitors of human phospholipase A(2)enzymes. |
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