Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08OCL
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| Former ID |
DNC014610
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| Drug Name |
4-(5-Nitro-indol-1-ylmethyl)-benzamidine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C16H14N4O2
|
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| Canonical SMILES |
C1=CC(=CC=C1CN2C=CC3=C2C=CC(=C3)[N+](=O)[O-])C(=N)N
|
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| InChI |
1S/C16H14N4O2/c17-16(18)12-3-1-11(2-4-12)10-19-8-7-13-9-14(20(21)22)5-6-15(13)19/h1-9H,10H2,(H3,17,18)
|
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| InChIKey |
TYZQZZRAPZQXLG-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Trypsin | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Pancreatic secretion | |||||
| Protein digestion and absorption | |||||
| Influenza A | |||||
| Reactome | Activation of Matrix Metalloproteinases | ||||
| Cobalamin (Cbl, vitamin B12) transport and metabolism | |||||
| WikiPathways | Activation of Matrix Metalloproteinases | ||||
| References | |||||
| REF 1 | J Med Chem. 1983 Feb;26(2):294-8.Aromatic amidines: comparison of their ability to block respiratory syncytial virus induced cell fusion and to inhibit plasmin, urokinase, thrombin, and trypsin. | ||||
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