Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0I9PA
|
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| Former ID |
DNC009635
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| Drug Name |
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)pyridine
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C13H11NO2
|
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| Canonical SMILES |
C1COC2=C(O1)C=CC(=C2)C3=CN=CC=C3
|
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| InChI |
1S/C13H11NO2/c1-2-11(9-14-5-1)10-3-4-12-13(8-10)16-7-6-15-12/h1-5,8-9H,6-7H2
|
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| InChIKey |
WBKBSDQNOSGKCC-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Cytochrome P450 11B1, mitochondrial | Target Info | Inhibitor | [1] | |
| BioCyc Pathway | Superpathway of steroid hormone biosynthesis | ||||
| Glucocorticoid biosynthesis | |||||
| Mineralocorticoid biosynthesis | |||||
| KEGG Pathway | Steroid hormone biosynthesis | ||||
| Metabolic pathways | |||||
| PathWhiz Pathway | Steroidogenesis | ||||
| Reactome | Glucocorticoid biosynthesis | ||||
| Endogenous sterols | |||||
| WikiPathways | Metapathway biotransformation | ||||
| Oxidation by Cytochrome P450 | |||||
| Metabolism of steroid hormones and vitamin D | |||||
| Corticotropin-releasing hormone | |||||
| References | |||||
| REF 1 | J Med Chem. 2008 Dec 25;51(24):8077-87.In vivo active aldosterone synthase inhibitors with improved selectivity: lead optimization providing a series of pyridine substituted 3,4-dihydro-1H-quinolin-2-one derivatives. | ||||
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