Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0L2AO
|
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| Former ID |
DNC014893
|
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| Drug Name |
DIHYDROXANTHOHUMOL
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C21H24O5
|
||||
| Canonical SMILES |
CC(=CCC1=C(C=C(C(=C1O)C(=O)CCC2=CC=C(C=C2)O)OC)O)C
|
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| InChI |
1S/C21H24O5/c1-13(2)4-10-16-18(24)12-19(26-3)20(21(16)25)17(23)11-7-14-5-8-15(22)9-6-14/h4-6,8-9,12,22,24-25H,7,10-11H2,1-3H3
|
||||
| InChIKey |
SVTCZHIDEDUTBH-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Calpain | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Protein processing in endoplasmic reticulum | ||||
| Apoptosis | |||||
| Alzheimer's disease | |||||
| Reactome | Degradation of the extracellular matrix | ||||
| WikiPathways | Focal Adhesion | ||||
| Integrated Pancreatic Cancer Pathway | |||||
| Alzheimers Disease | |||||
| Integrin-mediated Cell Adhesion | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). | ||||
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