Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0L2UQ
|
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| Former ID |
DNCL003496
|
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| Drug Name |
Pracinostat
|
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| Drug Type |
Small molecular drug
|
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| Indication | Myelodysplastic syndrome; Myelofibrosis [ICD9: 238.7, 208.9, 289.83, 709.2; ICD10:D46, C94.4, D47.4] | Phase 2 | [1], [2] | ||
| Company |
MEI Pharma
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C20H30N4O2
|
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| InChI |
InChI=1S/C20H30N4O2/c1-4-7-8-19-21-17-15-16(10-12-20(25)22-26)9-11-18(17)24(19)14-13-23(5-2)6-3/h9-12,15,26H,4-8,13-14H2,1-3H3,(H,22,25)/b12-10+
|
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| InChIKey |
JHDKZFFAIZKUCU-ZRDIBKRKSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
104253187, 121142796, 124757307, 125164111, 131480903, 134964553, 135264258, 136340267, 136359913, 136367450, 136920413, 137055167, 137390461, 140705810, 152258538, 160647372, 162011419, 162037638, 162202712, 163668154, 164193974, 172659608, 174520548, 174531534, 185973726, 188899586, 198945398, 202535654, 223366695, 223388553, 223705232, 227106278, 251963214, 252110018, 252160441, 252166577, 252216278, 252451771
|
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| Target and Pathway | |||||
| Target(s) | Histone deacetylase | Target Info | Modulator | [1] | |
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8365). | ||||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026393) | ||||
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