| Drug General Information |
| Drug ID |
D0L5EW
|
| Former ID |
DNC014040
|
| Drug Name |
(6-Ethoxy-2-naphthyl)-2-aminopropane
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C15H19NO
|
| Canonical SMILES |
CCOC1=CC2=C(C=C1)C=C(C=C2)CC(C)N
|
| InChI |
1S/C15H19NO/c1-3-17-15-7-6-13-9-12(8-11(2)16)4-5-14(13)10-15/h4-7,9-11H,3,8,16H2,1-2H3
|
| InChIKey |
RIBPBDJODPIITD-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Amine oxidase [flavin-containing] A |
Target Info |
Inhibitor |
[1]
|
|---|
| Amine oxidase [flavin-containing] B |
Target Info |
Inhibitor |
[1]
|
|
BioCyc Pathway
|
Superpathway of tryptophan utilization
|
|
Dopamine degradation
|
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Putrescine degradation III
|
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Noradrenaline and adrenaline degradation
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Serotonin degradation
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Superpathway of melatonin degradation
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Melatonin degradation IIPWY66-401:Superpathway of tryptophan utilization
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Tryptophan degradation via tryptamine
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KEGG Pathway
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Glycine, serine and threonine metabolism
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Arginine and proline metabolism
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Histidine metabolism
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Tyrosine metabolism
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Phenylalanine metabolism
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Tryptophan metabolism
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Drug metabolism - cytochrome P450
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Metabolic pathways
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Serotonergic synapse
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Dopaminergic synapse
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Cocaine addiction
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Amphetamine addiction
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Alcoholismhsa00260:Glycine, serine and threonine metabolism
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Alcoholism
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NetPath Pathway
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IL4 Signaling Pathway
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PANTHER Pathway
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Adrenaline and noradrenaline biosynthesis
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5-Hydroxytryptamine degredation
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Dopamine receptor mediated signaling pathwayP00001:Adrenaline and noradrenaline biosynthesis
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Dopamine receptor mediated signaling pathway
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Pathway Interaction Database
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Alpha-synuclein signaling
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PathWhiz Pathway
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Histidine Metabolism
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Tyrosine Metabolism
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Glycine and Serine Metabolism
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Reactome
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Norepinephrine Neurotransmitter Release Cycle
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WikiPathways
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SIDS Susceptibility Pathways
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Biogenic Amine Synthesis
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Oxidative Stress
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Dopamine metabolism
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Phase 1 - Functionalization of compounds
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Neurotransmitter Release Cycle
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Neurotransmitter Clearance In The Synaptic Cleft
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Serotonin Transporter ActivityWP465:Tryptophan metabolism
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| References |
| REF 1 | Bioorg Med Chem. 2009 Mar 15;17(6):2452-60. Epub 2009 Feb 8.Naphthylisopropylamine and N-benzylamphetamine derivatives as monoamine oxidase inhibitors. |
|---|
