| Drug General Information |
| Drug ID |
D0P4KF
|
| Former ID |
DNC005068
|
| Drug Name |
2-(4-tert-Butyl-phenyl)-4,5-dihydro-1H-imidazole
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C13H18N2
|
| Canonical SMILES |
CC(C)(C)C1=CC=C(C=C1)C2=NCCN2
|
| InChI |
1S/C13H18N2/c1-13(2,3)11-6-4-10(5-7-11)12-14-8-9-15-12/h4-7H,8-9H2,1-3H3,(H,14,15)
|
| InChIKey |
JRUYKUSXUFPDNO-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Alpha-1A adrenergic receptor |
Target Info |
Inhibitor |
[1]
|
|---|
| 5-hydroxytryptamine 1D receptor |
Target Info |
Inhibitor |
[1]
|
|
KEGG Pathway
|
Calcium signaling pathway
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cGMP-PKG signaling pathway
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Neuroactive ligand-receptor interaction
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AMPK signaling pathway
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Adrenergic signaling in cardiomyocytes
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Vascular smooth muscle contraction
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Salivary secretionhsa04024:cAMP signaling pathway
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Serotonergic synapse
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PANTHER Pathway
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Alpha adrenergic receptor signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
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5HT1 type receptor mediated signaling pathway
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Reactome
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Adrenoceptors
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G alpha (q) signalling events
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G alpha (12/13) signalling eventsR-HSA-390666:Serotonin receptors
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G alpha (i) signalling events
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WikiPathways
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Monoamine GPCRs
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Calcium Regulation in the Cardiac Cell
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GPCRs, Class A Rhodopsin-like
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Gastrin-CREB signalling pathway via PKC and MAPK
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Endothelin Pathways
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GPCR ligand binding
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GPCR downstream signaling
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AMPK SignalingWP722:Serotonin HTR1 Group and FOS Pathway
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| References |
| REF 1 | Bioorg Med Chem Lett. 2004 Sep 20;14(18):4697-9.2-(Anilino)imidazolines and 2-(benzyl)imidazoline derivatives as h5-HT1D serotonin receptor ligands. |
|---|
