Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0T8JU
|
||||
| Former ID |
DNC010509
|
||||
| Drug Name |
1-(4-Methoxybenzyl)-5-phenyl-1H-imidazole
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C17H16N2O
|
||||
| Canonical SMILES |
COC1=CC=C(C=C1)CN2C=NC=C2C3=CC=CC=C3
|
||||
| InChI |
1S/C17H16N2O/c1-20-16-9-7-14(8-10-16)12-19-13-18-11-17(19)15-5-3-2-4-6-15/h2-11,13H,12H2,1H3
|
||||
| InChIKey |
AZQFSYIIRUWICT-UHFFFAOYSA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Cytochrome P450 11B1, mitochondrial | Target Info | Inhibitor | [1] | |
| BioCyc Pathway | Superpathway of steroid hormone biosynthesis | ||||
| Glucocorticoid biosynthesis | |||||
| Mineralocorticoid biosynthesis | |||||
| KEGG Pathway | Steroid hormone biosynthesis | ||||
| Metabolic pathways | |||||
| PathWhiz Pathway | Steroidogenesis | ||||
| Reactome | Glucocorticoid biosynthesis | ||||
| Endogenous sterols | |||||
| WikiPathways | Metapathway biotransformation | ||||
| Oxidation by Cytochrome P450 | |||||
| Metabolism of steroid hormones and vitamin D | |||||
| Corticotropin-releasing hormone | |||||
| References | |||||
| REF 1 | J Med Chem. 2010 Feb 25;53(4):1712-25.Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.