Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0W9ZV
|
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| Former ID |
DNC014895
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| Drug Name |
AW-00430
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C14H10BrClN2O2S3
|
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| Canonical SMILES |
CC1=NC(=CS1)C2=CC=C(S2)S(=O)(=O)NC3=C(C=C(C=C3)Br)Cl
|
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| InChI |
1S/C14H10BrClN2O2S3/c1-8-17-12(7-21-8)13-4-5-14(22-13)23(19,20)18-11-3-2-9(15)6-10(11)16/h2-7,18H,1H3
|
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| InChIKey |
AMNKYHFERGWVCB-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Calpain | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Protein processing in endoplasmic reticulum | ||||
| Apoptosis | |||||
| Alzheimer's disease | |||||
| Reactome | Degradation of the extracellular matrix | ||||
| WikiPathways | Focal Adhesion | ||||
| Integrated Pancreatic Cancer Pathway | |||||
| Alzheimers Disease | |||||
| Integrin-mediated Cell Adhesion | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). | ||||
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