Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0XQ6V
|
||||
| Former ID |
DIB016523
|
||||
| Drug Name |
APD-515
|
||||
| Synonyms |
ACA-1515
|
||||
| Indication | Xerostomia [ICD9: 527.7; ICD10:K11.7, R68.2] | Phase 2 | [1] | ||
| Company |
Acacia Pharma Ltd
|
||||
| Target and Pathway | |||||
| Target(s) | Muscarinic receptor | Target Info | Agonist | [2] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| cAMP signaling pathway | |||||
| Neuroactive ligand-receptor interaction | |||||
| PI3K-Akt signaling pathway | |||||
| Cholinergic synapse | |||||
| Regulation of actin cytoskeleton | |||||
| PathWhiz Pathway | Muscle/Heart Contraction | ||||
| Reactome | Muscarinic acetylcholine receptors | ||||
| Acetylcholine regulates insulin secretion | |||||
| G alpha (q) signalling events | |||||
| WikiPathways | Monoamine GPCRs | ||||
| Calcium Regulation in the Cardiac Cell | |||||
| Regulation of Actin Cytoskeleton | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Secretion of Hydrochloric Acid in Parietal Cells | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033659) | ||||
| REF 2 | Clinical pipeline report, company report or official report of Acacia Pharma. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.