Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Z8EI
|
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| Former ID |
DNC004022
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| Drug Name |
6-Allyloxy-9H-purin-2-ylamine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C8H9N5O
|
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| Canonical SMILES |
C=CCOC1=NC(=NC2=C1NC=N2)N
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| InChI |
1S/C8H9N5O/c1-2-3-14-7-5-6(11-4-10-5)12-8(9)13-7/h2,4H,1,3H2,(H3,9,10,11,12,13)
|
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| InChIKey |
HJMGFQNIHIHSCQ-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Methylated-DNA--protein-cysteine methyltransferase | Target Info | Inhibitor | [1] | |
| WikiPathways | DNA Damage Reversal | ||||
| References | |||||
| REF 1 | J Med Chem. 2000 Nov 2;43(22):4071-83.Resistance-modifying agents. 8. Inhibition of O(6)-alkylguanine-DNA alkyltransferase by O(6)-alkenyl-, O(6)-cycloalkenyl-, and O(6)-(2-oxoalkyl)guanines and potentiation of temozolomide cytotoxicity in vitro by O(6)-(1-cyclopentenylmethyl)guanine. | ||||
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