Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0K5OZ
|
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| Former ID |
DIB018926
|
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| Drug Name |
AZ3971
|
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| Synonyms |
AZ 3971; AZ-3971
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C25H22N6O
|
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| InChI |
InChI=1S/C25H22N6O/c1-15-9-20(10-16(2)22(15)32-3)25(23-21(24(26)31-25)29-7-8-30-23)19-6-4-5-17(11-19)18-12-27-14-28-13-18/h4-14H,1-3H3,(H2,26,31)/t25-/m0/s1
|
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| InChIKey |
BICGYFRWDDPYEI-VWLOTQADSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Beta-secretase | Target Info | Inhibitor | [2] | |
| References | |||||
| REF 1 | Combining an amyloid-beta (Abeta) cleaving enzyme inhibitor with a gamma-secretase modulator results in an additive reduction of Abeta production. FEBS J. 2015 Jan;282(1):65-73. | ||||
| REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2330). | ||||
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