| Drug General Information |
| Drug ID |
D07VJT
|
| Former ID |
DNC008024
|
| Drug Name |
[6,3''']biflavone
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C30H18O4
|
| Canonical SMILES |
C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=CC(=C3)C4=CC(=CC=C4)C5=<br />CC(=O)C6=CC=CC=C6O5
|
| InChI |
1S/C30H18O4/c31-25-17-30(33-27-12-5-4-11-23(25)27)22-10-6-9-20(15-22)21-13-14-28-24(16-21)26(32)18-29(34-28)19-7-2-1-3-8-19/h1-18H
|
| InChIKey |
ATBFVHXRFRVXOQ-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Cytosolic phospholipase A2 |
Target Info |
Inhibitor |
[1]
|
|---|
|
BioCyc Pathway
|
Phospholipases
|
|
KEGG Pathway
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Glycerophospholipid metabolism
|
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Ether lipid metabolism
|
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Arachidonic acid metabolism
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Linoleic acid metabolism
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alpha-Linolenic acid metabolism
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Metabolic pathways
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MAPK signaling pathway
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Ras signaling pathway
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Vascular smooth muscle contraction
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VEGF signaling pathway
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Platelet activation
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Fc epsilon RI signaling pathway
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Fc gamma R-mediated phagocytosis
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Glutamatergic synapse
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Serotonergic synapse
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Long-term depression
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Inflammatory mediator regulation of TRP channels
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GnRH signaling pathway
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Ovarian steroidogenesis
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Oxytocin signaling pathway
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Choline metabolism in cancer
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NetPath Pathway
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TCR Signaling Pathway
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PANTHER Pathway
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Angiogenesis
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Endothelin signaling pathway
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Inflammation mediated by chemokine and cytokine signaling pathway
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Oxidative stress response
|
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VEGF signaling pathway
|
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CCKR signaling map ST
|
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Pathway Interaction Database
|
Fc-epsilon receptor I signaling in mast cells
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Endothelins
|
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PDGFR-beta signaling pathway
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Signaling mediated by p38-alpha and p38-beta
|
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PathWhiz Pathway
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Fc Epsilon Receptor I Signaling in Mast Cells
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Reactome
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Acyl chain remodelling of PC
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Acyl chain remodelling of PE
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Acyl chain remodelling of PI
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ADP signalling through P2Y purinoceptor 1
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Platelet sensitization by LDL
|
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WikiPathways
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Prostaglandin Synthesis and Regulation
|
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p38 MAPK Signaling Pathway
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Glycerophospholipid biosynthesis
|
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Arachidonic acid metabolism
|
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PDGF Pathway
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Integrated Pancreatic Cancer Pathway
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AGE/RAGE pathway
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Opioid Signalling
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Signal amplification
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Platelet homeostasis
|
| References |
| REF 1 | Bioorg Med Chem. 2007 Nov 15;15(22):7138-43. Epub 2007 Aug 22.Inhibitory effect of synthetic C-C biflavones on various phospholipase A(2)s activity. |
|---|
