Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D06KFR
|
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| Former ID |
DIB003528
|
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| Drug Name |
RP-73163
|
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| Drug Type |
Small molecular drug
|
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| Indication | Arteriosclerosis [ICD9: 440; ICD10:I70] | Terminated | [1] | ||
| Company |
Rhone-Poulenc SA
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C26H30N4OS
|
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| Canonical SMILES |
c1(nc(c([nH]1)c1ccccc1)c1ccccc1)[S@@](=O)CCCCCn1nc(cc1C<br />)C
|
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| CAS Number |
CAS 154461-48-0
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Liver carboxylesterase | Target Info | Modulator | [2] | |
| KEGG Pathway | Drug metabolism - other enzymes | ||||
| Metabolic pathways | |||||
| Pathway Interaction Database | E2F transcription factor network | ||||
| WikiPathways | NRF2 pathway | ||||
| Nuclear Receptors Meta-Pathway | |||||
| Heroin metabolism | |||||
| Irinotecan Pathway | |||||
| Fluoropyrimidine Activity | |||||
| Phase I biotransformations, non P450 | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003588) | ||||
| REF 2 | Hypolipidaemic properties of a potent and bioavailable alkylsulphinyl-diphenylimidazole ACAT inhibitor (RP 73163) in animals fed diets low in cholesterol. Biochem Pharmacol. 1996 Oct 25;52(8):1177-86. | ||||
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