| Drug General Information |
| Drug ID |
D0XC1F
|
| Former ID |
DIB000161
|
| Drug Name |
CX-9051
|
| Synonyms |
CX-9051; J-13016; COX-2 inhibitors (cancer); COX-2 inhibitors (cancer), National Taiwan University
|
| Indication |
Cancer [ICD9: 140-229; ICD10:C00-C96]
|
Investigative |
[1]
|
|---|
| Company |
National Taiwan University
|
| Structure |
|
Download
2D MOL
3D MOL
|
| Canonical SMILES |
O=S1(=O)N=S(c2ccc(cc12)[N+](=O)[O-])c1ccc(cc1)Br
|
| Target and Pathway |
| Target(s) |
Prostaglandin G/H synthase 2 |
Target Info |
Inhibitor |
[1]
|
|---|
|
BioCyc Pathway
|
Aspirin-triggered lipoxin biosynthesis
|
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Aspirin triggered resolvin D biosynthesis
|
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C20 prostanoid biosynthesis
|
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Aspirin triggered resolvin E biosynthesis
|
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KEGG Pathway
|
Arachidonic acid metabolism
|
|
Metabolic pathways
|
|
NF-kappa B signaling pathway
|
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VEGF signaling pathway
|
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TNF signaling pathway
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Retrograde endocannabinoid signaling
|
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Serotonergic synapse
|
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Ovarian steroidogenesis
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Oxytocin signaling pathway
|
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Regulation of lipolysis in adipocytes
|
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Leishmaniasis
|
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Pathways in cancer
|
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Chemical carcinogenesis
|
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MicroRNAs in cancer
|
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Small cell lung cancer
|
|
NetPath Pathway
|
IL1 Signaling Pathway
|
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TSH Signaling Pathway
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IL4 Signaling Pathway
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TGF_beta_Receptor Signaling Pathway
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IL5 Signaling Pathway
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PANTHER Pathway
|
Endothelin signaling pathway
|
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Inflammation mediated by chemokine and cytokine signaling pathway
|
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Toll receptor signaling pathway
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CCKR signaling map ST
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Pathway Interaction Database
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Calcineurin-regulated NFAT-dependent transcription in lymphocytes
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S1P1 pathway
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C-MYB transcription factor network
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Signaling mediated by p38-alpha and p38-beta
|
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Calcium signaling in the CD4+ TCR pathway
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PathWhiz Pathway
|
Arachidonic Acid Metabolism
|
|
WikiPathways
|
Prostaglandin Synthesis and Regulation
|
|
Arachidonic acid metabolism
|
|
Aryl Hydrocarbon Receptor
|
|
Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis
|
|
Spinal Cord Injury
|
|
Integrated Pancreatic Cancer Pathway
|
|
Eicosanoid Synthesis
|
|
Selenium Micronutrient Network
|
| References |
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1376). |
|---|
