Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01MYN
|
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| Former ID |
DIB011357
|
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| Drug Name |
LY-2523199
|
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| Synonyms |
11-beta hydroxysteroid dehydrogenase type 1 inhibitor (diabetes), Eli Lilly; 11-beta-HSD-1 inhibitor (type 2 diabetes), Eli Lilly
|
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| Indication | Type 2 diabetes [ICD9: 250; ICD10:E11] | Discontinued in Phase 2 | [1] | ||
| Company |
Eli Lilly & Co
|
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| Target and Pathway | |||||
| Target(s) | Corticosteroid 11-beta-dehydrogenase, isozyme 1 | Target Info | Inhibitor | [2] | |
| KEGG Pathway | Steroid hormone biosynthesis | ||||
| Metabolism of xenobiotics by cytochrome P450 | |||||
| Metabolic pathways | |||||
| Chemical carcinogenesis | |||||
| NetPath Pathway | IL1 Signaling Pathway | ||||
| FSH Signaling Pathway | |||||
| PathWhiz Pathway | Steroidogenesis | ||||
| Reactome | Glucocorticoid biosynthesis | ||||
| WikiPathways | Prostaglandin Synthesis and Regulation | ||||
| Metabolism of steroid hormones and vitamin D | |||||
| Glucocorticoid & Mineralcorticoid Metabolism | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034519) | ||||
| REF 2 | Repurposing Diabetes Drugs for Brain Insulin Resistance in Alzheimer Disease. before print June 15, 2014. | ||||
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