| Drug General Information |
| Drug ID |
D06SEA
|
| Former ID |
DIB000190
|
| Drug Name |
CX-7000
|
| Synonyms |
Second generation CK2 inhibitors (cancer), Cylene
|
| Indication |
Cancer [ICD9: 140-229; ICD10:C00-C96]
|
Investigative |
[1]
|
|---|
| Company |
Cylene Pharmaceuticals Inc
|
| Target and Pathway |
| Target(s) |
Casein kinase II, alpha chain |
Target Info |
Inhibitor |
[1]
|
|---|
|
KEGG Pathway
|
Ribosome biogenesis in eukaryotes
|
|
NF-kappa B signaling pathway
|
|
Wnt signaling pathway
|
|
Adherens junction
|
|
Tight junction
|
|
Measles
|
|
Herpes simplex infection
|
|
Epstein-Barr virus infection
|
|
NetPath Pathway
|
FSH Signaling Pathway
|
|
Pathway Interaction Database
|
BCR signaling pathway
|
|
Atypical NF-kappaB pathway
|
|
DNA-PK pathway in nonhomologous end joining
|
|
Presenilin action in Notch and Wnt signaling
|
|
Role of Calcineurin-dependent NFAT signaling in lymphocytes
|
|
E-cadherin signaling in the nascent adherens junction
|
|
Lissencephaly gene (LIS1) in neuronal migration and development
|
|
PDGFR-alpha signaling pathway
|
|
Signaling mediated by p38-alpha and p38-beta
|
|
Alpha-synuclein signaling
|
|
Reactome
|
Condensation of Prometaphase Chromosomes
|
|
WikiPathways
|
Mitotic Prometaphase
|
|
BDNF signaling pathway
|
|
TNF alpha Signaling Pathway
|
|
L1CAM interactions
|
| References |
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1549). |
|---|
