| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T71192 | ||||
| Target Name | Cysteinyl leukotriene receptor 1 | ||||
| Target Type | Successful |
||||
| Drug Potency against Target | Zafirlukast | Drug Info | IC50 = 600 nM | [553273] | |
| Pranlukast | Drug Info | IC50 = 300 nM | [553273] | ||
| References | |||||
| Ref 553273 | Effects of the cysteinyl leukotriene receptor antagonists pranlukast and zafirlukast on tracheal mucus secretion in ovalbumin-sensitized guinea-pigs in vitro. Br J Pharmacol. 1998 Jun;124(3):563-71. | ||||
| Ref 553273 | Effects of the cysteinyl leukotriene receptor antagonists pranlukast and zafirlukast on tracheal mucus secretion in ovalbumin-sensitized guinea-pigs in vitro. Br J Pharmacol. 1998 Jun;124(3):563-71. | ||||
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