Target Validation Information
Target ID T56915
Target Name HIV protease
Target Type
Successful
Drug Potency against Target Saquinavir Drug Info EC50 = 14 nM [552442]
Ritonavir Drug Info EC50 = 68 nM [552442]
Tipranavir Drug Info Ki = 1 nM [552443]
Amprenavir Drug Info EC50 = 78 nM [552442]
Indinavir Drug Info EC50 = 41 nM [552442]
References
Ref 552442Peptidomimetic inhibitors of HIV protease. Curr Top Med Chem. 2004;4(10):1079-95.
Ref 552442Peptidomimetic inhibitors of HIV protease. Curr Top Med Chem. 2004;4(10):1079-95.
Ref 552443Non-peptidic HIV protease inhibitors. Curr Top Med Chem. 2004;4(10):1097-114.
Ref 552442Peptidomimetic inhibitors of HIV protease. Curr Top Med Chem. 2004;4(10):1079-95.
Ref 552442Peptidomimetic inhibitors of HIV protease. Curr Top Med Chem. 2004;4(10):1079-95.

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