Target Validation Information | |||||
---|---|---|---|---|---|
Target ID | T35445 | ||||
Target Name | Mothers against decapentaplegic homolog 3 | ||||
Target Type | Successful |
||||
Drug Potency against Target | GNF-PF-2272 | Drug Info | IC50 = 38 nM | [531262] | |
FLUORESCEIN | Drug Info | IC50 = 4890 nM | [531262] | ||
ELLAGIC ACID | Drug Info | IC50 = 142 nM | [531262] | ||
References | |||||
Ref 531262 | Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). | ||||
Ref 531262 | Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). | ||||
Ref 531262 | Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). |
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