Target Validation Information
Target ID T35445
Target Name Mothers against decapentaplegic homolog 3
Target Type
Successful
Drug Potency against Target GNF-PF-2272 Drug Info IC50 = 38 nM [531262]
FLUORESCEIN Drug Info IC50 = 4890 nM [531262]
ELLAGIC ACID Drug Info IC50 = 142 nM [531262]
References
Ref 531262Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2).
Ref 531262Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2).
Ref 531262Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2).

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