| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T11843 | ||||
| Target Name | Vitamin K epoxide reductase complex subunit 1 | ||||
| Target Type | Successful |
||||
| Drug Potency against Target | Phenprocoumon | Drug Info | ED50 = 100~300 uM | [552443] | |
| Dicumarol | Drug Info | Ki = 600 nM | [552597] | ||
| References | |||||
| Ref 552443 | Non-peptidic HIV protease inhibitors. Curr Top Med Chem. 2004;4(10):1097-114. | ||||
| Ref 552597 | Development and validation of an in silico P450 profiler based on pharmacophore models. Curr Drug Discov Technol. 2006 Mar;3(1):1-48. | ||||
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