| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T56035 | ||||
| Target Name | CGMP-dependent protein kinase | ||||
| Target Type | Research |
||||
| Drug Potency against Target | TENELLONE B | Drug Info | IC50 = 8700 nM | [527524] | |
| STAUROSPORINONE | Drug Info | IC50 = 650 nM | |||
| TENELLONE A | Drug Info | IC50 = 12600 nM | [527524] | ||
| References | |||||
| Ref 527524 | J Nat Prod. 2005 Apr;68(4):611-3.Tenellones A and B from a Diaporthe sp.: two highly substituted benzophenone inhibitors of parasite cGMP-dependent protein kinase activity. | ||||
| Ref 527524 | J Nat Prod. 2005 Apr;68(4):611-3.Tenellones A and B from a Diaporthe sp.: two highly substituted benzophenone inhibitors of parasite cGMP-dependent protein kinase activity. | ||||
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