Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T00239 | Target Info | |||
| Target Name | Interleukin-4 (IL4) | ||||
| Synonyms |
Pitrakinra; Lymphocyte stimulatory factor 1; IL-4; Binetrakin; BSF-1; B-cell stimulatory factor 1
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| Target Type | Clinical trial Target | ||||
| Gene Name | IL4 | ||||
| Biochemical Class | Cytokine: interleukin | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Arachidonate 5-lipoxygenase (5-LOX) | Successful Target | ||||
| UniProt ID | LOX5_HUMAN | |||||
| Gene Name | ALOX5 | |||||
| Synonyms |
LOG5; 5-lipoxygenase; 5-LO
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| Representative Drug(s) | Tepoxalin | Drug Info | EC50 = 70 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Benzothiazole hydroxy ureas as inhibitors of 5-lipoxygenase: use of the hydroxyurea moiety as a replacement for hydroxamic acid. J Med Chem. 1992 Aug 21;35(17):3180-3. | ||||
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