Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T02702 | Target Info | |||
| Target Name | Bacterial Dihydrofolate reductase (Bact DHFR) | ||||
| Synonyms |
Bact Dihydrofolate reductase
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| Target Type | Clinical trial Target | ||||
| Gene Name | Bact DHFR | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Dihydrofolate reductase (DHFR) | Successful Target | ||||
| UniProt ID | DYR_HUMAN | |||||
| Gene Name | DHFR | |||||
| Synonyms |
DYR; DHFRP1
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| Representative Drug(s) | Iclaprim | Drug Info | IC50 = 8 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Iclaprim, a novel diaminopyrimidine with potent activity on trimethoprim sensitive and resistant bacteria. Bioorg Med Chem Lett. 2003 Dec 1;13(23):4217-21. | ||||
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