Co-Target(s) Information

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Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T07289 Target Info
Target Name Duffy antigen chemokine receptor (ACKR1)
Synonyms
Plasmodium vivax receptor; GpFy; Glycoprotein D; Fy glycoprotein; Duffy antigen/chemokine receptor; DARC; CD234; ACKR1
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Target Type Successful Target
Gene Name ACKR1
Biochemical Class GPCR duffy
UniProt ID
ACKR1_HUMAN
Co-Targets of This Target  Top
Co-Target Name Plasmodium Cysteine protease falcipain-2 (Malaria CPF2) Literature-reported Target
UniProt ID Q9N6S8_PLAFA
Gene Name Malaria CPF2
Synonyms
Falcipain 2; Cysteine proteinase falcipain 2a
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Representative Drug(s) Drug Info IC50 = 20 nM [1]
References  Top
REF 1 Designing novel inhibitors against falcipain-2 of Plasmodium falciparum. Bioorg Med Chem Lett. 2018 May 15;28(9):1566-1569.

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