Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T21678 | Target Info | |||
| Target Name | Alpha-galactosidase A (GLA) | ||||
| Synonyms |
Melibiase; INN=Agalsidase; Alpha-D-galactoside galactohydrolase; Alpha-D-galactosidase A
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| Target Type | Successful Target | ||||
| Gene Name | GLA | ||||
| Biochemical Class | Glycosylase | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Sucrase-isomaltase (SI) | Co-Target | ||||
| UniProt ID | SUIS_HUMAN | |||||
| Gene Name | SI | |||||
| Synonyms |
Sucrase-isomaltase, intestinal
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| Representative Drug(s) | Migalastat | Drug Info | IC50 = 260 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Dual-action lipophilic iminosugar improves glycemic control in obese rodents by reduction of visceral glycosphingolipids and buffering of carbohydrate assimilation. J Med Chem. 2010 Jan 28;53(2):689-98. | ||||
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