Co-Target(s) Information

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Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T38301 Target Info
Target Name Ribonucleoside-diphosphate reductase M2 (RRM2)
Synonyms
Ribonucleotide reductase small subunit; Ribonucleotide reductase small chain; Ribonucleoside-diphosphate reductase subunit M2; RR2
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Target Type Successful Target
Gene Name RRM2
Biochemical Class CH/CH(2) oxidoreductase
UniProt ID
RIR2_HUMAN
Co-Targets of This Target  Top
Co-Target Name CDGSH iron-sulfur domain-containing protein 1 (CISD1_HUMAN) Co-Target
UniProt ID CISD1_HUMAN
Gene Name CISD1
Synonyms
MitoNEET
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Representative Drug(s) Triapine Drug Info Ki = 388 nM [1]
References  Top
REF 1 Identification of small molecules that bind to the mitochondrial protein mitoNEET. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5350-5353.

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