Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T59604 | Target Info | |||
| Target Name | Growth hormone secretagogue receptor 1 (GHSR) | ||||
| Synonyms |
Growth hormone secretagogue receptor; Ghrelin receptor; GHSR; GHS-R; GHRP; GH-releasing peptide receptor
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| Target Type | Successful Target | ||||
| Gene Name | GHSR | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Ghrelin (GHRL) | Clinical trial Target | ||||
| UniProt ID | GHRL_HUMAN | |||||
| Gene Name | GHRL | |||||
| Synonyms |
UNQ524/PRO1066; Motilin-related peptide; M46 protein; Growth hormone secretagogue; Growth hormone releasing peptide; Gastric peptide ghrelin; GHRL
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| Representative Drug(s) | Drug Info | Ki = 16 nM | [1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Optimization of the potency and pharmacokinetic properties of a macrocyclic ghrelin receptor agonist (Part I): Development of ulimorelin (TZP-101) from hit to clinic. J Med Chem. 2011 Dec 22;54(24):8305-20. | ||||
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