Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T96235 | Target Info | |||
| Target Name | Glutamate receptor AMPA 4 (GRIA4) | ||||
| Synonyms |
Glutamate receptor ionotropic, AMPA 4; GluRD; GluR4; GluA4; GRIA4; AMPAselective glutamate receptor 4
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| Target Type | Successful Target | ||||
| Gene Name | GRIA4 | ||||
| Biochemical Class | Glutamate-gated ion channel | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Glutamate receptor AMPA 1 (GRIA1) | Successful Target | ||||
| UniProt ID | GRIA1_HUMAN | |||||
| Gene Name | GRIA1 | |||||
| Synonyms |
Glutamate receptor ionotropic, AMPA 1; Glutamate receptor 1; GluR-K1; GluR-A; GluR-1; GluA1; GLUR1; GLUH1; AMPA-selective glutamate receptor 1
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| Representative Drug(s) | Drug Info | IC50 = 243 nM | [1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Discovery of the First alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) -8. J Med Chem. 2016 May 26;59(10):4753-68. | ||||
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