Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02DQT
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| Former ID |
DIB019317
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| Drug Name |
PMID11934595C2
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| Synonyms |
GTPL8562; BDBM50111848; E8S
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C22H22N2O7S2
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| Canonical SMILES |
COC1=CC=C(C=C1)S(=O)(=O)N(CC2=CC3=C(C=C2)OCO3)C(CC4=CC=CS4)C(=O)NO
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| InChI |
1S/C22H22N2O7S2/c1-29-16-5-7-18(8-6-16)33(27,28)24(13-15-4-9-20-21(11-15)31-14-30-20)19(22(25)23-26)12-17-3-2-10-32-17/h2-11,19,26H,12-14H2,1H3,(H,23,25)/t19-/m1/s1
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| InChIKey |
PGEHBYYTLWHQOM-LJQANCHMSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bone morphogenetic protein 1 (BMP1) | Target Info | Inhibitor | [1] |
| Panther Pathway | TGF-beta signaling pathway | |||
| Reactome | Degradation of the extracellular matrix | |||
| Collagen biosynthesis and modifying enzymes | ||||
| Anchoring fibril formation | ||||
| WikiPathways | Cardiac Progenitor Differentiation | |||
| Adipogenesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Amino acid derived sulfonamide hydroxamates as inhibitors of procollagen C-proteinase. Part 2: Solid-phase optimization of side chains. Bioorg Med Chem Lett. 2002 Apr 22;12(8):1233-5. | |||
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