Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02TNS
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| Former ID |
DIB014721
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| Drug Name |
TMC-353121
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| Synonyms |
JNJ-2408068; R-170591; Viral fusion inhibitor (RSV infection), J&J; Viral fusion inhibitor (respiratory syncytial virus infection), J&J
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| Drug Type |
Small molecular drug
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| Indication | Respiratory syncytial virus infection [ICD-11: 1C80; ICD-9: 79.6] | Preclinical | [1] | |
| Company |
Johnson & Johnson
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| Structure |
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Download2D MOL |
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| Formula |
C32H42N6O3
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| Canonical SMILES |
CC1=CC(=C(C=C1)CCCO)NCC2=CC3=C(C=C2)N=C(N3CC4=C(C=CC(=N4)C)O)NCCCN5CCOCC5
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| InChI |
1S/C32H42N6O3/c1-23-6-9-26(5-3-16-39)28(19-23)34-21-25-8-10-27-30(20-25)38(22-29-31(40)11-7-24(2)35-29)32(36-27)33-12-4-13-37-14-17-41-18-15-37/h6-11,19-20,34,39-40H,3-5,12-18,21-22H2,1-2H3,(H,33,36)
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| InChIKey |
DKORMNNYNRPTBJ-UHFFFAOYSA-N
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| CAS Number |
CAS 857066-90-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Respiratory syncytial virus protein F (RSV F) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027151) | |||
| REF 2 | Prospects for the development of fusion inhibitors to treat human respiratory syncytial virus infection. Curr Opin Drug Discov Devel. 2009 Jul;12(4):479-87. | |||
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