Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03GVL
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| Former ID |
DNC013070
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| Drug Name |
6-aza-uridine monophosphate
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| Synonyms |
6-Aza-ump; 6-Azauridine-5'-monophosphate; 6-aza uridine 5'-monophosphate; 1los; UP6; [(2R,3S,4R,5R)-5-(3,5-dioxo-1,2,4-triazin-2-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate; aza UMP; 6-Azauridine-5'-phosphate; 6-Azauridine 5'M; NSC47549; 6-Azauridine 5'MP; 6-azauridine 5'-phosphate; AC1L45DF; 6-aza-uridine monophosphate; C6-Uridine Derivative, 18; 6-Azauridine-5-monophosphate; CHEMBL463480; SCHEMBL3214622; BDBM21340; 6-Azauridine 5'-phosphoric acid; ZINC12503861; AKOS027381721; DB03718; W-201761
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C8H12N3O9P
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| Canonical SMILES |
C1=NN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)O)O)O
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| InChI |
1S/C8H12N3O9P/c12-4-1-9-11(8(15)10-4)7-6(14)5(13)3(20-7)2-19-21(16,17)18/h1,3,5-7,13-14H,2H2,(H,10,12,15)(H2,16,17,18)/t3-,5-,6-,7-/m1/s1
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| InChIKey |
LRVZOSYMNMNQFR-SHUUEZRQSA-N
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| CAS Number |
CAS 2018-19-1
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:46319
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Mycobacterium Orotidine phosphate decarboxylase (MycB pyrF) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Design of inhibitors of orotidine monophosphate decarboxylase using bioisosteric replacement and determination of inhibition kinetics. J Med Chem. 2006 Aug 10;49(16):4937-45. | |||
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