Drug Information
Drug General Information | Top | |||
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Drug ID |
D0B8CU
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Former ID |
DNC003362
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Drug Name |
AL7182
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Synonyms |
AL7182; 3,,4-dihydro-2-(3-methoxyphenyl)-2h-thieno-[3,2-e]-1,2-thiazine-6-sulfonamide-1,1-dioxide; 1bnn; AC1L1BTX; SCHEMBL678649; CHEMBL331858; BDBM11935; DB02602; AL-7182; 2-(3-Methoxyphenyl)-6-sulfamoyl-3,4-dihydro-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide; 2-(3-methoxyphenyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide; 2-(3-methoxyphenyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide; 2-(3-methoxyphenyl)-1,1-dioxo-3H,4H-1$l^{6},7,2-thieno[3,2-e][1$l^{6},2]thiazine-6-sulfonamide
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C13H14N2O5S3
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Canonical SMILES |
COC1=CC=CC(=C1)N2CCC3=C(S2(=O)=O)SC(=C3)S(=O)(=O)N
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InChI |
1S/C13H14N2O5S3/c1-20-11-4-2-3-10(8-11)15-6-5-9-7-12(22(14,16)17)21-13(9)23(15,18)19/h2-4,7-8H,5-6H2,1H3,(H2,14,16,17)
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InChIKey |
ICIXQGGQPKFQRL-UHFFFAOYSA-N
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Carbonic anhydrase II (CA-II) | Target Info | Inhibitor | [1] |
KEGG Pathway | Nitrogen metabolism | |||
Proximal tubule bicarbonate reclamation | ||||
Collecting duct acid secretion | ||||
Gastric acid secretion | ||||
Pancreatic secretion | ||||
Bile secretion | ||||
NetPath Pathway | IL4 Signaling Pathway | |||
EGFR1 Signaling Pathway | ||||
Reactome | Erythrocytes take up carbon dioxide and release oxygen | |||
Erythrocytes take up oxygen and release carbon dioxide | ||||
Reversible hydration of carbon dioxide | ||||
WikiPathways | Reversible Hydration of Carbon Dioxide | |||
Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | ||||
Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes |
References | Top | |||
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REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
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