Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0S5LS
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| Former ID |
DNC003373
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| Drug Name |
N-(2,6-Diflouro-Benzyl)-4-Sulfamoyl-Benzamide
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| Synonyms |
N-[(2,6-difluorophenyl)methyl]-4-sulfamoylbenzamide; n-(2,6-diflouro-benzyl)-4-sulfamoyl-benzamide; n-(2,6-difluoro-benzyl)-4-sulfamoyl-benzamide; F6B; 2,6-difluoro-SBB; AC1L1HTT; SCHEMBL678297; BDBM12019; 1g53; 1g48; DB03844; N-(2,6-Difluorobenzyl)-4-sulfamoylbenzamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H12F2N2O3S
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| Canonical SMILES |
C1=CC(=C(C(=C1)F)CNC(=O)C2=CC=C(C=C2)S(=O)(=O)N)F
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| InChI |
1S/C14H12F2N2O3S/c15-12-2-1-3-13(16)11(12)8-18-14(19)9-4-6-10(7-5-9)22(17,20)21/h1-7H,8H2,(H,18,19)(H2,17,20,21)
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| InChIKey |
ZFNCKGXGCCDDFN-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase II (CA-II) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Nitrogen metabolism | |||
| Proximal tubule bicarbonate reclamation | ||||
| Collecting duct acid secretion | ||||
| Gastric acid secretion | ||||
| Pancreatic secretion | ||||
| Bile secretion | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| EGFR1 Signaling Pathway | ||||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | |||
| Erythrocytes take up oxygen and release carbon dioxide | ||||
| Reversible hydration of carbon dioxide | ||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | |||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | ||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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