Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0T9NZ
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| Former ID |
DNC002690
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| Drug Name |
Glutathionylspermidine Disulfide
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| Synonyms |
GLUTATHIONYLSPERMIDINE DISULFIDE; TS4; AC1L9N8X; DB02553; (2R)-2-amino-5-[[(2R)-1-[[2-[3-(4-aminobutylamino)propylamino]-2-oxoethyl]amino]-3-[[(2R)-3-[[2-[3-(4-aminobutylamino)propylamino]-2-oxoethyl]amino]-2-[[(4R)-4-amino-5-hydroxy-5-oxopentanoyl]amino]-3-oxopropyl]disulfanyl]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C34H66N12O10S2
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| Canonical SMILES |
C(CCNCCCNC(=O)CNC(=O)C(CSSCC(C(=O)NCC(=O)NCCCNCCCCN)NC(=O)CCC(C(=O)O)N)NC(=O)CCC(C(=O)O)N)CN
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| InChI |
1S/C34H66N12O10S2/c35-11-1-3-13-39-15-5-17-41-29(49)19-43-31(51)25(45-27(47)9-7-23(37)33(53)54)21-57-58-22-26(46-28(48)10-8-24(38)34(55)56)32(52)44-20-30(50)42-18-6-16-40-14-4-2-12-36/h23-26,39-40H,1-22,35-38H2,(H,41,49)(H,42,50)(H,43,51)(H,44,52)(H,45,47)(H,46,48)(H,53,54)(H,55,56)/t23-,24-,25+,26+/m1/s1
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| InChIKey |
HCMZDPYSWPSKSP-XPGKHFPBSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutathione reductase (GR) | Target Info | Inhibitor | [1] |
| BioCyc | Glutathione redox reactions II | |||
| Glutathione redox reactions I | ||||
| KEGG Pathway | Glutathione metabolism | |||
| Thyroid hormone synthesis | ||||
| Pathwhiz Pathway | Glutamate Metabolism | |||
| Glutathione Metabolism | ||||
| WikiPathways | Metapathway biotransformation | |||
| Sulfation Biotransformation Reaction | ||||
| Oxidative Stress | ||||
| NRF2 pathway | ||||
| Nuclear Receptors Meta-Pathway | ||||
| Selenium Micronutrient Network | ||||
| Glutathione metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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